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Coding Region: Introns and Exons (EK FL 1: #159)

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So...I took EK FL 1 and am doing my post-game analysis. There is a discrete which states:

Beta-thallasemia is a genetic disorder characterized by decreased levels of a functional beta chain in hemoglobin. This disorder is caused by a single nucleotide change in a coding portion of the gene that is not included in the mature mRNA transcript. How is this possible?

B) Point mutations in exons changing the final structure so beta chain is nonfunctional
C) Point mutations in introns causing...

Coding Region: Introns and Exons (EK FL 1: #159)

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